The Global Janus Kinase Inhibitor Market Continues To Grow Owing To the Increased Demand from Healthcare Organizations to Treat Conditions Such As SLE and Increasing Investment in the R&D Sector

 

Janus Kinase Inhibitor Market

Janus Kinase Inhibitor is one of the most promising newly-developed anti-neurotransmitter drugs that is developed for treating diseases that involve the neuroendocrine system, the pituitary gland, and other glands and organ systems. The drug specifically affects the production of neuropeptide Y, a chemical neurotransmitter in the brain that is involved in regulating mood, anxiety, and sexuality.

Janus Kinase Inhibitor works by inhibiting the action of one or perhaps more of the family of neurotransmitters, thereby interfering with the neurotransmitter signaling pathway. Neurotransmitters are chemical messages sent from one nerve cell to another, which typically include dopamine, epinephrine, norepinephrine, and serotonin. When these neurotransmitters are broken down by Janus Kinase Inhibitor, the brain does not receive the neurotransmitter message that it normally needs for normal functioning. This is believed to underlie the depression, anxiety, and mood disorders that many of these neurotransmitter inhibitors have been shown to relieve. One of the proposed mechanisms for how the Janus Kinase Inhibitor work is by preventing the entry of calcium into the synaptic vesicles of the affected neurons, which is a necessary step in the formation of long-term memories.

Market Dynamics                                               

The main factor driving the Janus Kinase Inhibitor market is the rapid inclination towards industrial researches related to immune response and signaling. For instance, in Jun2 2018, U.S. Food and Drug Administration (FDA) approved OLUMIANT (baricitinib), developed by Eli Lilly and Company. It is an oral medicine for treating rheumatoid arthritis in adults. Moreover, key manufacturers and several research organizations are also focusing on the research and development of better Janus Kinase Inhibitor drugs.

However, the high cost associated with the drugs and the treatments is the main restraining factor hindering the growth of the Janus Kinase Inhibitor market.

This market is distributed in five regions that include North America, Asia-Pacific, Europe, Africa, and the Middle East, and Latin America. Among these, North America is estimated to hold a significant share of the Janus Kinase Inhibitor market owing to a high prevalence of systemic lupus erythematosus (SLE) in the region. For instance, according to the Lupus Foundation of America, 1.5 million U.S. residents suffer from SLE, and among them, 90% are mostly women. The Janus Kinase Inhibitor market in Asia-Pacific is expected to witness a significant rise owing to the increased awareness related to health conditions such as SLE in the region, backed by favorable government health policies and adoption of advanced technology in the healthcare sectors.

Competitive Analysis

Key players operating in the global Janus kinase inhibitor market include Incyte Corporation, CTI BioPharma Corp., Sierra Oncology, Inc., Gilead Sciences Inc., Novartis International AG, Baxter International Inc., Pfizer Inc.,  Astellas Pharma Inc., and Eli Lilly and Company.

In February 2021, SHR0302, a Janus kinase type 1 (JAK1) inhibitor developed by Reistone Biopharma Co. Ltd. cleared the Phase 2 Clinical Study.


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