Increasing Prevalence of Cardiovascular Diseases to Augment Growth of Acute Heart Failure (AHF) Therapeutics Market

 

Acute heart failure is a medical emergency that involves sudden, permanent cessation of cardiac function (also called ventricular fibrillation). Acute heart failure most often develops due to a rupture or leaky blood vessel somewhere in the heart. This can happen either at the heart site itself, such as at the coronary artery, or at the lung level, such as at the aortic valve. As a result of the rupture, blood is pooling at the heart site and the blood flow is markedly reduced. As this pooling continues, blood pressure drops causing a decrease in cardiac output and, as the problem worsens, shock and death occur.

Market Dynamics

Increasing prevalence of cardiovascular diseases is expected to propel growth of the global acute heart failure (AHF) therapeutics market. For instance, according to the American Heart Association's Heart and Stroke Statistics 2020 Update, by 2035, 45.1% of the U.S population is projected to have some form of cardiovascular disease. Moreover, increasing geriatric population is also expected to aid in growth of the market. For instance, according to United Nations Population Fund, geriatric population in Asia Pacific is expected to triple between 2010 and 2050 to reach 1.3 billion people by 2050.

High prevalence of heart failure is also expected to propel growth of the global acute heart failure (AHF) therapeutics market. For instance, according to the study, ‘Global epidemiology and future trends of heart failure’, published in AME Medical Journal in June 2020, heart failure poses the largest burden after 60 years of age and both prevalence and YLDs have increased by 3.9% and 4.5% in very elderly people during the last 28 years. Moreover, R&D in acute heart failure (AHF) therapeutics is also expected to aid in growth in the market. For instance, in November 2020, a clinical trial by Brigham and Women's Hospital and sponsored by Lexicon Pharmaceuticals, a biopharmaceutical company based in the U.S., reported that sotagliflozin, a combination sodium/glucose cotransporter 1 and 2 (SGLT1/2) inhibitor, resulted in a lower risk of the composite of deaths from cardiovascular causes, hospitalizations for heart failure, and urgent visits for heart failure than placebo.

Competitive Analysis

Major players operating in the acute heart failure (AHF) therapeutics market include, Novartis AG, Cardiorentis AG, Bristol-Myers Squibb Company, Amgen Inc., Bayer AG, Cytokinetics, Inc., Merck & Company, Inc., Ono Pharmaceutical Co., Ltd., and Pfizer Inc., among others.


Location: India

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